Original Article
 
Complications of acute pancreatitis in tertiary care hospital
Soubia Akhter1, Zaeem UR Rehman Khan1, Bilal Ahmed1, Farah Ahmed1, Zahid Ali Memon1
1Dow University of health and sciences, Karachi, Pakistan.

Article ID: 100069IJHPDSA2017
doi:10.5348/ijhpd-2017-69-OA-5

Address correspondence to:
Farah Ahmed
Dow University of health and sciences
Karachi 74200
Pakistan

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How to cite this article:
Akhter S, UR Rehman Khan Z, Ahmed B, Ahmed F, Memon ZA. Complications of acute pancreatitis in tertiary care hospital. Int J Hepatobiliary Pancreat Dis 2017;7:23–27.


Abstract
Aims: The aim of this study was to determine the complications of acute pancreatitis in tertiary care hospital.
Methods: Hundred patients diagnosed with acute pancreatitis were analyzed in this prospective cohort study from July 2015 to July 2016. Complications were studied. Cholelithiasis was found to be the most common cause of acute pancreatitis in our setting.
Results: Acute pancreatitis is defined as reversible inflammation of pancreatic parenchyma which is characterized by the presence of interstitial edema, acute inflammatory cell infiltrate and varying degree of cellular apoptosis, necrosis and hemorrhage. Cholelithiasis and alcohol were found to be the most common causes of acute pancreatitis. Alcohol, Smoking, some medications are the major risk factors. The major complications of acute pancreatitis are pseudocyst, pleural effusion, sepsis, shock or internal bleeding, fluid collection, ascites.
Conclusion: Acute pancreatitis is one of the most common gastrointestinal ailments with high morbidity and mortality worldwide and at our set up too. Like any other disease occurrence of complications may worsen the prognosis of acute pancreatitis. Acute fluid collection around pancreas came out to be the common complication.

Keywords: Acute disease, Acute pancreatitis, Amylase, Alcohol cholelithiasis, Inflammation

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Author Contributions
Soubia Akhter – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Zaeem Ur Rehman Khan – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Bilal Ahmed – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Farah Ahmed – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Zahid Ali Memon – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Group 3- Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2017 Soubia Akhter et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.