Case Report
 
Metronidazole induced neurotoxicity in a case of liver abscess
Pushpa Kumari1, Yogesh Chandra Porwal2, Aanchal Arora3, Manish Kumar4, Dilip Kumar5
1MBBS MD, Assistant Professor, Department of medicine, VMMC and Safdarjung hospital, New Delhi, 110029, India.
2MBBS MD, Consultant and Professor, Department of medicine, VMMC and Safdarjung Hospital, New Delhi 110029, India.
3MBBS MD, Senior Resident, Department of medicine, VMMC and Safdarjung Hospital, New Delhi, 110029, India.
4MBBS, Junior Resident, Department of medicine, VMMC and Safdarjung Hospital, New Delhi 110029, India.
5MBBS MD, Consultant and Head, Department of medicine, VMMC and Safdarjung Hospital, New Delhi 110029, India.

Article ID: 100061IJHPDRZ2016
doi:10.5348/ijhpd-2016-61-CR-17

Address correspondence to:
Pushpa Kumari
Flat no.79, Ajanta Apartment
Patparganj
New Delhi
India, 110092

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How to cite this article:
Kumari P, Porwal YC, Arora A, Kumar M, Kumar D. Metronidazole induced neurotoxicity in a case of liver abscess. Int J Hepatobiliary Pancreat Dis 2016;6:96–99.


Abstract
Metronidazole is a commonly used drug and considered relatively safe. But it may present with neurotoxicity, commonly peripheral and rarely central. We report here a case of a young patient with amoebic liver abscess who continued taking metronidazole longer than the prescribed duration of the drug and developed peripheral neuropathy and cerebellar neurotoxicity which was reversible after discontinuation of the drug.

Keywords: Ataxia, Liver abscess, Metronidazole, Neurotoxicity


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Author Contributions
Pushpa Kumari – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Yogesh Chandra Porwal – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Aanchal Arora – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Manish Kumar – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Dilip Kumar – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Pushpa Kumari et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.