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Research Article
Application of magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography in biliary obstruction
1 Assistant Professor, Department of Gastroenterology of Xuancheng People’s Hospital, Xuancheng, China
2 The second year Postgraduate student of Bengbu Medical University, Department of Gastroenterology of Xuancheng People’s Hospital, Xuancheng
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Zheng Zhou
Xuancheng People’s Hospital, Xuancheng City, Anhui Province 242000,
China
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Article ID: 100109Z04ZZ2026
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How to cite this article
Zhou Z, Wu HY. Application of magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography in biliary obstruction. Int J Hepatobiliary Pancreat Dis 2026;16(1):1–7.ABSTRACT
Introduction: Biliary obstruction is a common clinical disease, and magnetic resonance cholangiopancreatography (MRCP) and endoscopic retrograde cholangiopancreatography (ERCP) play an important role in the diagnosis and treatment of biliary obstruction. This study explores the localization, qualitative diagnosis, and treatment effects of MRCP and ERCP on biliary obstruction diseases.
Methods: Retrospective analysis of patients diagnosed with biliary obstruction who underwent MRCP examination and ERCP treatment from October 2022 to October 2024. The patients were divided into jaundice group and non-jaundice group according to their clinical characteristics. The clinical characteristics, treatment, and accuracy of localization and qualitative diagnosis of the two groups were analyzed.
Results: A total of 78 patients with biliary obstruction who underwent MRCP examination and ERCP treatment were collected, with 39 cases in jaundice group and 39 cases in the non-jaundice group. The total bilirubin level and alkaline phosphatase (ALT) level in the jaundice group were significantly lower than those before surgery, with significant differences. In terms of localization and qualitative diagnosis in both the jaundice group and non-jaundice group, the results indicate that the combination of MRCP and ERCP has a high accuracy rate for the localization and qualitative diagnosis of biliary obstruction.
Conclusion: In the diagnosis of biliary obstruction diseases, MRCP and ERCP have their own advantages and disadvantages. By combining the strengths of both, accuracy of localization and qualitative diagnosis of biliary obstruction can be improved to some extent. In terms of treatment, the bilirubin and ALT levels in the jaundice group improved significantly after ERCP, indicating that ERCP is more effective in patients with biliary obstruction complicated with jaundice.
Keywords: Endoscopic retrograde cholangiopancreatography (ERCP), Localization and qualitative diagnosis, Magnetic resonance cholangiopancreatography (MRCP),
Zheng Zhou and HaiYan Wu are co-first authors.
SUPPORTING INFORMATION
Author Contributions
Zheng Zhou - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
HaiYan Wu - Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2026 Zheng Zhou et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
