Table of Contents    
Review Article
 
A review of transplantation for tumors other than hepatocellular carcinoma
Ryan Ruel T Barroso1, Daniel Cherqui2,
1Department of Surgery, Cardinal Santos Medical Center, San Juan, Manila, Philippines.
2Chief - Section of Hepatobiliary Surgery & Liver Transplantation New York Presbyterian - Weill Cornell Medical College, New York, USA.

Article ID: 100008IJHPDRRTB2012
doi:10.5348/ijhpd-2012-8-RA-6

Address correspondence to:
Ryan Ruel T Barroso, MD
Rm 215, Medical Arts Bldg, Cardinal Santos Medical Center
Wilson St., San Juan
Manila
Philippines
Phone: +63 9175540024
Email: RyeBarroso@gmail.com

[HTML Full Text]   [PDF Full Text]

How to cite this article:
Barroso RRT, Cherqui D. A review of transplantation for tumors other than hepatocellular carcinomat. International Journal of Hepathobiliary and Pancreatic Diseases 2012;2:24–30.


Abstract
Introduction: Debates are ongoing in many centers for the indications of liver transplantation for non-hepatocellular carcinoma tumors due to a number of factors. Standardized protocols are lacking and clinical outcomes vary.
Objective: A review was performed of the numerous published articles, with focus on the management and clinical outcome of tumors besides hepatocellular carcinoma (HCC) which were treated by liver transplantation, namely, cholangiocarcinoma, neuroendocrine tumors and hepatic epitheloid hemangioendothelioma in an attempt to promote a more standardized guideline.
Discussion: Liver transplantation for cholangiocarcinoma reveals promising results in selected group of patients who underwent neoadjuvant chemoradiation prior to transplantation. For neuroendocrine tumors with liver metastases a number of selection criteria have been proposed in different centers, however the results of which are still variable. Transplantation is a viable option for unresectable hepatic epitheloid hemangioepithelioma with results at par with resection.
Conclusion: Over time as patient selection, techniques, peri-operative care and the understanding of the different diseases improves, the results of liver transplantation for these tumors likewise will became favourable. However, standardization of the management and guidelines are still needed.

Key Words: Liver Transplant, Cholangiocarcinoma, Neuroendocrine Tumors, Hepatic Epitheloid Hemangioepithelioma, Clinical Outcome.

[HTML Full Text]   [PDF Full Text]

Author Contributions:
Ryan Ruel Tupas Barroso - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Daniel Cherqui - Conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Critical revision of the article, Final approval of the version to be published
Guarantor of submission:
The corresponding author is the guarantor of submission.
Source of support:
None
Conflict of interest:
Authors declare no conflict of interest.
Copyright:
© Ryan Ruel Tupas Barroso et al. 2012 This article is distributed the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any means provided the original authors and original publisher are properly credited. (Please see Copyright Policy for more information.)